Group Based Trajectory Model for Hippocampal Sclerosis and Alzheimer's
disease
 
   Lead Investigator:    Xiuhua Ding
   Institution      :    Department of Biostatistics
   E-Mail           :    xiuhua.ding@uky.edu
   Proposal ID      :    531



   Proposal Description:
   The goal of the proposed research is to apply group based trajectory model to distinguish two ageing disease ???Hippocampal sclerosis (HS) and Alzheimer disease (AD). As known, the two types of disease share very similar clinical characteristics, but they are neuropathologically different. It is important to distinguish them from each other clinically. Using group based trajectory modeling, we aim to examine the underline trajectory of cognitive impairment overtime for the HS subjects and AD subjects, and evaluate whether the group based trajectory model have better prediction of the two group memberships.